5 Factors That Trigger Type 2 Diabetes In Obese People

Factors That Trigger Type 2 Diabetes In Obese People

It’s an oft repeated fact that our health is directly linked to the size of our waist. Being obese puts us at an increased risk of developing a series of health related issues. One such risk is Type II Diabetes. Type II diabetes is a condition in which there is an abnormal surge in the glucose levels in the blood due to an impaired insulin production in the body or because the body becomes resistant to insulin. Let us take a look at the factors that play a role in making obesity a leading cause of type II diabetes.

Here Are 5 Factors That Trigger Type 2 Diabetes In Obese People

Rise In Free Fatty Acids

Obese people have a high adipose tissue mass which is responsible for a surge in the production of Plasma Non-sterified Fatty Acids or free fatty acids in the body. This rise in free fatty acids signals the muscles and the liver to become insulin resistant and thus leads to the development of type II diabetes.


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fatty acids

Endoplasmic Recticulum Stress

Endoplasmic Recticulum is a network of membranes within the cells whose role is to derive, fold, transport and process proteins in the body. When there is obesity, there is inflammation in the adipose tissue which then leads to Endoplasmic Recticulum ER) stress. ER stress occurs when unprocessed proteins begin to pile up in the ER. ER stress gives rise to an impaired glycemic control and insulin resistance and hence triggers type II diabetes.

 Stress

Release Of PEDF

Obesity is accompanied with a rise in the number of fat cells in the body. These cells release a protein called Pigment Epithelium Derived Factor (PEDF). When this protein enters the blood, it causes the liver and the muscles to become less receptive to insulin following which the pancreas overworks in order to produce more insulin and thus exhausts itself to the point when it’s no longer able to produce insulin. This inability to produce insulin is associated with the development of diabetes.

pedf

Hormone Resistin

The fat tissue is composed of cells called adipocytes which release a hormone known as resistin. This hormone plays a crucial role in causing the cells throughout the body to become insusceptible to insulin and is, therefore, a dominant factor in the progression of type II diabetes.

Hormone Resistin

Pro-Inflammatory Cytokines

The adipose tissue in overweight people expresses proteins known as cytokines which are responsible for the onset of inflammation within the adipose tissue. The inflamed adipose tissue is linked with the development of insulin susceptibility in the body which then manifests in the form of type II diabetes.

Diabetes

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    • Combines vitamins, minerals, antioxidants and other nutrients along with healthy hair, skin and nails support
    • This comprehensive and complete formula delivers a total of 36 nutrients comprising vitamins, minerals, antioxidants, health blends, amino acids in one convenient daily dose.
    • Contains Biotin for Healthy Hair Care.
    • Providing 100% RDA limits for maximum Vitamins & Mineral. Contains 13 Amino Acids. Helps support strong nails. Helps support lustrous hair.
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    • Fast-acting Whey Protein Isolate & Whey Protein Concentrate is the leading Protein source. Setting New Gold Standards 116.85 kcal Energy, 25g Protein, 0.85g Fat, 0g Sugar, 0023g Trans Fat Per 33g Serving. ZERO SUGAR!
    • Higher protein percentage (25g of protein, 88.45% Whey protein by weight). Enriched with Calcium, Sodium, Potassium and Amino Acids.
    • Includes Ultra-Filtered Whey for less cholesterol, fat & sodium. 5.84G BCAA's and 4.13g L-Glutamic Acid. Rich Double Chocolate Flavor. Instantized to Mix Easily Using a Glass and Spoon.
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    • PLEASE NOTE: MuscleXP Brand is owned by Emmbros Overseas. Across all Online Platforms, the orders are supplied directly by the company and therefore 100% original and does not require any authenticity check. None of the MuscleXP products come with any Printed Foil inside the Box. However, All Jars come with MuscleXP Printed Seal outside the Jar.
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